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重庆男子一家4口患肝癌

来源: 南方日报网络版     时间: 2019年05月21日 14:32:12
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(  渝)(北)(区)(一)(家)(四)(口)(都)(患)(有)(肝)(癌)(,其)(中)(3人)(已)(经)(死)(亡)(;沙)(坪)(坝)(区)(一)(名)(男)(子)(前)(后)(两)(任)(妻)(子)(都)(患)(上)(宫)(颈)(癌)(。近)(日)(,国)(外)(医)(学)(期)(刊)(《CancerCell》刊)(发)(研)(究)(论)(文)(称)(,癌)(细)(胞)(具)(有)(传)(染)(性)(。  在)(原)(有)(的)(认)(知)(中)(,癌)(症)(不)(具)(备)(任)(何)(传)(染)(性)(,即)(使)(最)(亲)(近)(的)(人)(患)(癌)(,也)(与)(自)(己)(的)(健)(康)(无)(关)(,但)(这)(种)(观)(点)(也)(许)(要)(改)(改)(了)(。  重)(庆)(晚)(报)(记)(者)(严)(艺)(菲)(  一)(家)(四)(口)(都)(有)(肝)(癌)(  谭)(先)(生)(家)(住)(渝)(北)(区)(人)(和)(镇)(万)(年)(路)(,包)(括)(自)(己)(在)(内)(的)(家)(中)(4个)(人)(都)(患)(上)(肝)(癌)(,其)(中)(妻)(子)(、儿)(子)(、丈)(母)(娘)(已)(经)(病)(逝)(。由)(于)(谭)(先)(生)(发)(现)(肝)(癌)(时)(已)(是)(晚)(期)(,50岁)(的)(他)(也)(已)(时)(日)(不)(多)(。  十)(多)(年)(前)(,谭)(先)(生)(的)(丈)(母)(娘)(去)(世)(,4年)(前)(儿)(子)(不)(治)(身)(亡)(。  2014年)(11月)(,妻)(子)(告)(诉)(谭)(先)(生)(,她)(的)(右)(上)(腹)(持)(续)(疼)(痛)(。两)(人)(来)(到)(肿)(瘤)(医)(院)(做)(检)(查)(,结)(果)(不)(出)(意)(料)(,又)(是)(肝)(癌)(,还)(是)(中)(晚)(期)(,肿)(块)(已)(经)(很)(大)(,医)(生)(说)(手)(术)(意)(义)(不)(大)(。两)(人)(早)(有)(心)(理)(准)(备)(,商)(量)(好)(住)(院)(治)(疗)(1个)(月)(就)(出)(院)(。  妻)(子)(住)(院)(期)(间)(,医)(生)(在)(查)(房)(时)(看)(到)(谭)(先)(生)(脸)(色)(蜡)(黄)(,问)(道)(,“你)(平)(时)(身)(体)(如)(何)(?”谭)(先)(生)(回)(答)(:“我)(腹)(部)(也)(时)(常)(会)(痛)(。”  医)(生)(让)(谭)(先)(生)(做)(肝)(癌)(筛)(查)(,结)(果)(显)(示)(,谭)(先)(生)(的)(右)(上)(腹)(有)(一)(个)(13.5cm×11cm的)(肿)(块)(—肝)(癌)(晚)(期)(。  医)(生)(说)(法)(  接)(诊)(谭)(先)(生)(和)(妻)(子)(的)(医)(生)(是)(重)(庆)(市)(肿)(瘤)(医)(院)(肝)(胆)(外)(科)(副)(主)(任)(医)(师)(张)(杰)(峰)(,他)(告)(诉)(记)(者)(,80%肝)(癌)(患)(者)(患)(病)(诱)(因)(是)(乙)(肝)(病)(毒)(的)(传)(播)(,谭)(先)(生)(一)(家)(人)(都)(是)(乙)(肝)(患)(者)(,丈)(母)(娘)(由)(母)(婴)(血)(液)(渠)(道)(将)(乙)(肝)(病)(毒)(传)(给)(妻)(子)(,妻)(子)(再)(由)(母)(婴)(血)(液)(渠)(道)(将)(乙)(肝)(病)(毒)(传)(给)(儿)(子)(,而)(谭)(先)(生)(的)(乙)(肝)(病)(毒)(则)(来)(源)(于)(与)(妻)(子)(的)(性)(行)(为)(。  乙)(肝)(病)(毒)(最)(易)(引)(发)(肝)(癌)(,谭)(先)(生)(一)(家)(正)(是)(中)(了)(它)(的)(招)(。张)(杰)(峰)(说)(:“正)(因)(为)(这)(种)(传)(染)(现)(象)(,现)(在)(肝)(癌)(家)(族)(不)(少)(。不)(过)(由)(于)(观)(念)(陈)(旧)(,普)(通)(人)(还)(未)(引)(起)(重)(视)(。”  前)(后)(两)(任)(妻)(子)(宫)(颈)(癌)(  家)(住)(沙)(坪)(坝)(区)(的)(蒋)(先)(生)(今)(年)(40岁)(。5年)(前)(,他)(的)(第)(一)(任)(妻)(子)(患)(宫)(颈)(癌)(去)(世)(,如)(今)(他)(的)(第)(二)(任)(妻)(子)(也)(被)(诊)(断)(为)(宫)(颈)(癌)(晚)(期)(。  第)(一)(任)(妻)(子)(的)(去)(世)(,让)(蒋)(先)(生)(深)(感)(癌)(症)(的)(可)(怕)(。所)(幸)(在)(接)(下)(来)(的)(常)(规)(体)(检)(中)(,蒋)(先)(生)(身)(体)(无)(碍)(。  蒋)(先)(生)(37岁)(时)(,经)(人)(介)(绍)(认)(识)(了)(第)(二)(任)(妻)(子)(,恋)(爱)(1年)(后)(结)(婚)(。几)(个)(月)(前)(,第)(二)(任)(妻)(子)(在)(与)(蒋)(先)(生)(一)(次)(同)(房)(后)(,出)(现)(了)(与)(第)(一)(任)(妻)(子)(相)(似)(的)(症)(状)(:阴)(道)(持)(续)(出)(血)(,腰)(部)(持)(续)(疼)(痛)(。经)(过)(医)(院)(检)(查)(,结)(果)(是)(宫)(颈)(癌)(中)(晚)(期)(。  医)(生)(说)(法)(  接)(诊)(医)(生)(是)(重)(庆)(市)(肿)(瘤)(医)(院)(妇)(瘤)(科)(主)(任)(王)(冬)(。他)(介)(绍)(,宫)(颈)(癌)(患)(者)(99%以)(上)(都)(携)(带)(有)(HPV病)(毒)(,即)(人)(体)(乳)(头)(瘤)(病)(毒)(,一)(种)(球)(形)(DNA病)(毒)(,能)(引)(起)(人)(体)(皮)(肤)(黏)(膜)(的)(鳞)(状)(上)(皮)(增)(殖)(。  王)(冬)(说)(,HPV病)(毒)(抵)(抗)(力)(强)(,能)(耐)(受)(干)(燥)(并)(长)(存)(活)(,仅)(通)(过)(高)(温)(加)(热)(或)(经)(福)(尔)(马)(林)(处)(理)(才)(可)(灭)(活)(。该)(病)(毒)(传)(染)(途)(径)(多)(,包)(括)(性)(传)(播)(、密)(切)(接)(触)(、母)(婴)(产)(道)(传)(播)(。  另)(外)(,HPV病)(毒)(只)(对)(女)(性)(敏)(感)(,在)(由)(性)(行)(为)(感)(染)(到)(男)(性)(后)(除)(了)(可)(能)(提)(高)(男)(性)(生)(殖)(器)(癌)(发)(病)(率)(,一)(般)(不)(会)(产)(生)(任)(何)(症)(状)(,但)(HPV病)(毒)(却)(会)(通)(过)(感)(染)(男)(性)(,再)(传)(染)(给)(该)(男)(性)(的)(下)(一)(个)(女)(性)(伴)(侣)(,诱)(发)(宫)(颈)(癌)(。  研)(究)(:癌)(细)(胞)(具)(有)(传)(染)(性)(  关)(于)(癌)(症)(是)(否)(会)(传)(染)(,近)(日)(,《CancerCell》医)(学)(期)(刊)(发)(表)(论)(文)(称)(,乳)(腺)(癌)(外)(泌)(体)(能)(导)(致)(正)(常)(细)(胞)(变)(成)(肿)(瘤)(细)(胞)(,发)(现)(体)(外)(经)(过)(外)(泌)(体)(转)(化)(的)(正)(常)(细)(胞)(可)(以)(在)(小)(鼠)(体)(内)(产)(生)(肿)(瘤)(。  论)(文)(指)(出)(,癌)(症)(细)(胞)(会)(释)(放)(出)(自)(身)(产)(生)(的)(垃)(圾)(,这)(些)(垃)(圾)(可)(将)(附)(近)(的)(健)(康)(细)(胞)(转)(化)(成)(肿)(瘤)(细)(胞)(。癌)(细)(胞)(含)(有)(大)(量)(外)(泌)(体)(,即)(带)(有)(蛋)(白)(质)(、DNA和)(RNA的)(小)(型)(有)(膜)(结)(构)(,被)(认)(为)(是)(细)(胞)(的)(垃)(圾)(清)(除)(系)(统)(。一)(些)(外)(泌)(体)(可)(以)(与)(周)(围)(细)(胞)(融)(合)(,并)(将)(其)(携)(带)(的)(信)(息)(转)(移)(给)(该)(细)(胞)(。  据)(悉)(,外)(泌)(体)(由)(机)(体)(众)(多)(类)(型)(细)(胞)(释)(放)(,广)(泛)(分)(布)(于)(唾)(液)(、血)(浆)(、乳)(汁)(、尿)(液)(等)(体)(液)(当)(中)(。外)(泌)(体)(参)(与)(细)(胞)(通)(讯)(、细)(胞)(迁)(移)(、血)(管)(新)(生)(和)(肿)(瘤)(细)(胞)(生)(长)(等)(过)(程)(。研)(究)(发)(现)(,癌)(细)(胞)(比)(正)(常)(细)(胞)(释)(放)(更)(多)(的)(外)(泌)(体)(。  研)(究)(人)(员)(采)(集)(了)(8名)(健)(康)(人)(和)(11名)(乳)(腺)(癌)(患)(者)(的)(血)(液)(,11位)(癌)(症)(患)(者)(中)(5位)(的)(外)(泌)(体)(具)(有)(诱)(导)(正)(常)(细)(胞)(转)(化)(为)(肿)(瘤)(的)(作)(用)(,8位)(健)(康)(人)(的)(外)(泌)(体)(没)(有)(该)(作)(用)(。而)(外)(泌)(体)(可)(以)(在)(全)(身)(自)(由)(运)(输)(,且)(可)(以)(将)(健)(康)(细)(胞)(变)(成)(肿)(瘤)(细)(胞)(。研)(究)(说)(明)(癌)(症)(细)(胞)(具)(有)(一)(定)(传)(染)(性)(。  外)(泌)(体)(或)(成)(肿)(瘤)(治)(疗)(新)(方)(法)(  对)(于)(这)(项)(新)(研)(究)(,肿)(瘤)(医)(院)(肿)(瘤)(内)(科)(主)(任)(王)(东)(林)(解)(释)(,外)(泌)(体)(确)(实)(存)(在)(,因)(为)(不)(论)(是)(正)(常)(细)(胞)(还)(是)(癌)(细)(胞)(,都)(具)(有)(活)(细)(胞)(,会)(有)(内)(吞)(外)(排)(的)(机)(制)(进)(行)(物)(质)(传)(递)(,即)(具)(有)(能)(够)(影)(响)(周)(围)(细)(胞)(的)(旁)(分)(泌)(现)(象)(。  王)(东)(林)(说)(,该)(研)(究)(属)(于)(体)(外)(基)(础)(研)(究)(,离)(临)(床)(运)(用)(还)(有)(一)(段)(距)(离)(。如)(果)(可)(证)(实)(在)(人)(体)(内)(也)(确)(有)(其)(事)(,那)(就)(是)(颠)(覆)(性)(的)(发)(现)(。目)(前)(,癌)(症)(仅)(可)(能)(通)(过)(病)(毒)(传)(染)(诱)(发)(身)(边)(人)(的)(癌)(症)(,直)(接)(的)(癌)(细)(胞)(传)(染)(还)(未)(被)(证)(实)(。  王)(东)(林)(说)(,有)(正)(常)(免)(疫)(力)(的)(人)(,即)(使)(接)(触)(一)(定)(数)(量)(的)(癌)(细)(胞)(,也)(没)(事)(。但)(如)(果)(有)(免)(疫)(缺)(陷)(的)(人)(,则)(另)(当)(别)(论)(。  王)(东)(林)(认)(为)(,如)(果)(该)(研)(究)(被)(证)(实)(,至)(少)(有)(3点)(可)(以)(作)(为)(论)(题)(,一)(是)(癌)(症)(患)(者)(亲)(近)(者)(的)(防)(护)(;二)(是)(对)(肿)(瘤)(手)(术)(医)(生)(的)(保)(护)(;三)(是)(研)(究)(中)(提)(到)(癌)(细)(胞)(外)(泌)(体)(可)(以)(抑)(制)(癌)(细)(胞)(,也)(许)(是)(肿)(瘤)(治)(疗)(研)(究)(的)(新)(切)(入)(口)(。  病)(毒)(可)(能)(传)(染)(的)(癌)(症)(有)(哪)(些)(  王)(东)(林)(告)(诉)(记)(者)(,癌)(症)(病)(人)(身)(上)(的)(病)(毒)(可)(以)(让)(癌)(症)(具)(有)(传)(染)(性)(,这)(些)(病)(毒)(传)(染)(性)(高)(、途)(径)(多)(,是)(癌)(症)(的)(重)(要)(诱)(因)(。  王)(东)(林)(介)(绍)(,研)(究)(证)(明)(病)(毒)(可)(以)(通)(过)(多)(种)(生)(物)(学)(途)(径)(影)(响)(宿)(主)(细)(胞)(的)(生)(长)(、增)(殖)(与)(恶)(性)(转)(化)(。  致)(瘤)(病)(毒)(感)(染)(细)(胞)(后)(,可)(将)(它)(们)(的)(遗)(传)(物)(质)(永)(久)(性)(的)(整)(合)(进)(细)(胞)(基)(因)(组)(,是)(引)(起)(肿)(瘤)(发)(生)(的)(必)(需)(步)(骤)(之)(一)(。致)(瘤)(病)(毒)(控)(制)(宿)(主)(细)(胞)(酶)(系)(统)(,将)(病)(毒)(基)(因)(与)(细)(胞)(基)(因)(重)(组)(,从)(而)(使)(病)(毒)(基)(因)(插)(入)(到)(细)(胞)(基)(因)(的)(一)(个)(或)(多)(个)(位)(点)(。病)(毒)(癌)(基)(因)(插)(入)(到)(细)(胞)(基)(因)(组)(中)(,以)(剪)(切)(、重)(组)(表)(达)(的)(方)(式)(,产)(生)(致)(瘤)(蛋)(白)(产)(物)(激)(活)(癌)(基)(因)(,使)(宿)(主)(丧)(失)(基)(本)(的)(正)(常)(生)(物)(学)(特)(征)(,其)(分)(子)(机)(制)(是)(细)(胞)(周)(期)(紊)(乱)(引)(起)(的)(细)(胞)(无)(限)(增)(殖)(和)(凋)(亡)(抑)(制)(等)(。  王)(东)(林)(说)(:“正)(常)(细)(胞)(只)(有)(在)(某)(些)(致)(癌)(病)(毒)(的)(作)(用)(下)(,且)(当)(机)(体)(免)(疫)(功)(能)(降)(低)(或)(者)(遭)(受)(损)(害)(时)(,破)(坏)(了)(正)(常)(的)(细)(胞)(,使)(得)(癌)(基)(因)(被)(激)(活)(,癌)(细)(胞)(无)(限)(增)(殖)(,最)(终)(形)(成)(致)(命)(肿)(瘤)(。不)(过)(也)(不)(用)(恐)(慌)(,目)(前)(的)(研)(究)(显)(示)(,致)(瘤)(病)(毒)(可)(以)(传)(染)(,但)(肿)(瘤)(不)(会)(直)(接)(传)(染)(。”  宫)(颈)(癌)(  传)(染)(病)(毒)(:HPV人)(体)(乳)(头)(瘤)(病)(毒)(  传)(染)(途)(径)(:性)(传)(播)(途)(径)(、密)(切)(接)(触)(、间)(接)(接)(触)((通)(过)(感)(染)(者)(的)(衣)(物)(、生)(活)(用)(品)(、用)(具)(等)()、医)(源)(性)(感)(染)((医)(务)(人)(员)(在)(治)(疗)(护)(理)(时)(自)(身)(感)(染)()、母)(婴)(传)(播)((由)(婴)(儿)(通)(过)(孕)(妇)(产)(道)(的)(密)(切)(接)(触)()  预)(防)(:目)(前)(只)(有)(预)(防)(性)(的)(疫)(苗)(等)(可)(以)(预)(防)(4种)(HPV病)(毒)(类)(型)(感)(染)(。男)(性)(过)(长)(包)(皮)(的)(环)(切)(术)(是)(预)(防)(女)(性)(宫)(颈)(癌)(的)(重)(要)(措)(施)(,同)(时)(也)(是)(防)(止)(男)(性)(自)(身)(感)(染)(各)(类)(性)(病)(的)(重)(要)(措)(施)(。  肝)(癌)(  传)(染)(病)(毒)(:乙)(肝)(病)(毒)(  传)(染)(途)(径)(:血)(液)(传)(播)(、母)(婴)(传)(播)(、性)(传)(播)(  预)(防)(:及)(时)(注)(射)(疫)(苗)(,感)(染)(后)(积)(极)(治)(疗)(,注)(意)(注)(射)(、接)(种)(、文)(身)(等)(使)(用)(的)(各)(种)(医)(疗)(器)(具)(,性)(生)(活)(中)(使)(用)(安)(全)(套)(。  胃)(癌)(  传)(染)(细)(菌)(:幽)(门)(螺)(旋)(杆)(菌)(  传)(染)(途)(径)(:口)(对)(口)(传)(播)(、喷)(嚏)(传)(播)(  预)(防)(:有)(慢)(性)(胃)(炎)(的)(患)(者)(应)(避)(免)(口)(口)(喂)(养)(幼)(儿)(;患)(者)(在)(与)(人)(亲)(吻)(时)(也)(需)(注)(意)(;患)(者)(打)(喷)(嚏)(时)(,旁)(人)(应)(转)(身)(,保)(持)(1米)(距)(离)(。  鼻)(咽)(癌)(  传)(染)(病)(毒)(:EB病)(毒)(  传)(染)(途)(径)(:唾)(液)(传)(播)(  预)(防)(:接)(种)(EB疫)(苗)(,注)(意)(避)(免)(口)(对)(口)(传)(播)(和)(喷)(嚏)(飞)(沫)(传)(播)(。  肺)(癌)(手)(术)(  只)(在)(肋)(间)(  开)(个)(洞)(  重)(庆)(晚)(报)(讯)(肺)(叶)(切)(除)(手)(术)(中)(,需)(要)(在)(患)(者)(肋)(骨)(缝)(隙)(间)(开)(一)(条)(裂)(口)(,或)(开)(几)(个)(孔)(对)(肺)(部)(没)(用)(的)(东)(西)(进)(行)(清)(理)(,但)(这)(种)(常)(规)(手)(术)(会)(伴)(有)(剧)(烈)(痛)(感)(,并)(发)(症)(感)(染)(几)(率)(还)(不)(小)(。2014年)(12月)(29日)(,重)(庆)(医)(科)(大)(学)(附)(属)(第)(一)(医)(院)(完)(成)(市)(内)(首)(例)(单)(孔)(胸)(腔)(镜)(下)(肺)(癌)(根)(治)(术)(。  62岁)(的)(王)(先)(生)(家)(住)(江)(北)(区)(南)(桥)(寺)(,是)(一)(名)(拥)(有)(40年)(烟)(龄)(的)(老)(烟)(枪)(,每)(天)(要)(抽)(一)(包)(左)(右)(。去)(年)(11月)(,他)(被)(检)(查)(出)(患)(有)(肺)(癌)(。  重)(医)(附)(一)(院)(胸)(心)(外)(科)(主)(治)(医)(师)(陈)(丹)(告)(诉)(重)(庆)(晚)(报)(记)(者)(,王)(先)(生)(需)(要)(接)(受)(开)(胸)(手)(术)(治)(疗)(,并)(决)(定)(为)(他)(实)(施)(单)(孔)(胸)(腔)(镜)(下)(肺)(癌)(根)(治)(术)(。  12月)(29日)(,医)(生)(在)(患)(者)(右)(侧)(肋)(间)(隙)(处)(打)(了)(一)(个)(长)(4厘)(米)(左)(右)(的)(小)(孔)(,将)(其)(癌)(变)(的)(右)(肺)(下)(叶)(完)(全)(切)(除)(,并)(对)(肺)(门)(及)(纵)(隔)(淋)(巴)(结)(进)(行)(彻)(底)(清)(扫)(,整)(个)(手)(术)(出)(血)(量)(不)(到)(50毫)(升)(。经)(过)(近)(两)(小)(时)(的)(手)(术)(后)(,王)(先)(生)(现)(在)(恢)(复)(良)(好)(。  陈)(丹)(说)(,较)(之)(常)(规)(胸)(腔)(镜)(微)(创)(手)(术)(,进)(行)(单)(孔)(手)(术)(后)(,患)(者)(的)(疼)(痛)(感)(会)(降)(低)(60%左)(右)(;常)(规)(的)(手)(术)(后)(,患)(者)(需)(5到)(7天)(才)(能)(出)(院)(,进)(行)(单)(孔)(手)(术)(的)(患)(者)(3到)(5天)(即)(可)(出)(院)(;并)(发)(症)(感)(染)(的)(几)(率)(会)(降)(低)(一)(半)(。此)(外)(,单)(孔)(手)(术)(的)(费)(用)(跟)(常)(规)(手)(术)(费)(用)(一)(样)(。  重)(庆)(晚)(报)(记)(者)(赵)(帮)(清)(冉)(文)()!

作者:【龙虎和代理】


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